Companion Algorithms

Hematopathology

Hematopathology is the study of hematopoietic diseases including leukemias, lymphomas, mast cell neoplasms, plasma cell neoplasms and many others. Multiple tissue types are often reviewed including lymphoid tissues, bone marrow and blood. A wide range of tests are used in diagnosis including a variety of immunohistochemistry markers.

Multiple myeloma is a hematopoietic disease of plasma cells. Diagnosis criteria includes myeloma related organ dysfunction, monoclonal protein present in the blood or urine and presence of plasmacytoma or >10% plasma cells in the bone marrow1. Determination of plasma cell counts in bone marrow can be done using the CD138 antibody. BioImagene's CD138 algorithm* detects and counts CD138 labeled plasma cells in bone marrow samples. The algorithm displays results of percent positivity, and number of stained and unstained plasma cells.

*Ventana test systems are for in vitro diagnostic use for specific clinical applications, and are intended for research use only for other applications