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TissueMine™

Overview

TissueMine™ is a web based total digital pathology solution for research and development. It is a fully integrated, ready to use package that includes iScan™ - BioImagene’s new tissue slide scanner, high performance servers, storage systems and high resolution display terminal. TissueMine™ automates the pathology workflow improving efficiency and minimizing bottlenecks in an otherwise manual process. It provides a superior alternative to the traditional manual analysis of tissue slides through a microscope. Researchers, pathologists and toxico-pathologists can benefit from a rapid comprehensive analysis and management of tissue images from Tissue Micro Arrays (TMA) or whole tissue slides. TissueMine™ is built on the robust 3i™ image informatics platform.

 

Advantages | Features| TissueMine Packages| View PDF

 

 

 

 

 

 

 

 

 

Advantages:

Total solution for research and development

  • Complete solution for acquisition, analysis, management, reporting and sharing of tissue images
  • One touch, walk away automation
  • Batch processing capability accelerates the workflow and reduces analysis time from weeks and days, to hours and minutes

Fully integrated with iScanT Tissue Scanner

  • Autoloader with 160 slide capacity
  • High quality, high resolution images
  • High speed scanning of slides

Image viewing and annotation

  • Comprehensive annotation of images with measurement tools and textual annotations
  • Support for remote viewing and sharing of images

Comprehensive image analysis

  • Comprehensive analysis with over 30 morphological algorithms covering IHC, H&E, CISH and FISH.
  • User modifiable analysis parameters
  • Tissue morphology and pixel based analysis for specific tissue structures

Consistency in results

  • Standardizes the slide scoring process to produce an accurate, standardized, quantitative analysis that is consistent and repeatable
  • Eliminates inter observer and intra observer variability

Highly customizable and user friendly solution

  • Can be customized to meet unique user requirements
  • Easy to use software designed by pathologists
  • Better ergonomics for ease and comfort of the user

High Throughput TMA analysis

  • Optimized for acquisition, processing and analysis of images from TMA's( Tissue Micro Array)
  • Automatic gridding of TMAs.
  • TissueMine can accurately analyze a 100 core Tissue Micro Array (TMA) under 15 minutes. A similar manual analysis in comparison takes 3-4 days and is a tedious process subject to user variability

Overview | Features

 

TissueMine™ Features:

Image acquisition

  • Digitization of glass slides
  • Instrument independent. Acquires images from iScan™ and/or other acquisition devices including digital cameras and other slide scanners

Image management

  • Enables researchers to annotate, archive, analyze, search and share images
  • The saved analysis results are automatically stored in 3i™ for future queries
  • A powerful search engine can easily retrieve the analysis results along with the processed images

Morphology and intensity based image analysis

  • Supports CAP protocols
  • Over 30 morphological algorithms to cover assays like IHC, H&E, FISH and CISH
  • Supports nuclear / cytoplasm /membrane analysis
  • Automatic ROI identification
  • Quality assessment module to check for image quality variances

Personalization of analysis

  • GUI based calibration tool
  • The user can modify the analysis parameters for the algorithms without having to make software changes to the application
  • Users have the capability to refine feature identification and customize scoring criteria for accurate results

Report generation

  • Customizable report templates
  • Results can be easily exported to MicrosoftT programs like PowerpointT, WordT, ExcelT and statistical analysis tools like SAST and Spotfire™

Regulatory compliance

  • TissueMine™ is 21 CFR Part 11 compliant.
  • TissueMine™ supports audit trail, digital signatures, archive and retrieve features.

Telepathology / Virtual microscopy

  • Anytime, anywhere access to Images and data
  • Helps scientists around the world communicate, collaborate and share results
  • Facilitates virtual tumor boards, electronic white boards and worldwide communication

*For Research Use Only

TissueMine Packages

Package Components Express Desktop Workgroup Enterprise
iScanT Instrument N/A Scanner, Controller PC, Image Mgmt PC, and 24" LCD Monitor Scanner, Controller PC, Image Mgmt PC, and 24" LCD Monitor Scanner, Controller PC, Image Mgmt PC, and 24" LCD Monitor
iScanT Storage N/A ~300 slides ~3000 slides ~30k slides
iScan T Software N/A V,C,IM V,C,IM V,C,IM
License - Algorithm 5 perpetual 1 perpetual 5 perpetual 25 perpetual
License - iScanT Viewe N/A unlimited perpetual unlimited perpetual unlimited perpetual
License - iScanT Controller N/A 1 perpetual 1 perpetual 4 perpetual
License - iScanT Image Mgmt. N/A 1 perpetual 1 perpetual 4 perpetual
Algorithm Software TMA, NMC TMA, NMC TMA, NMC TMA,NMC (IHC,H&E and custom)

NMC: Nuclear, Membrane, Cytoplasm TMA: Tissue Micro Array, V,C,IM: Viewer, Controller, Image Management

 

Overview | Advantages

 

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